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Fingolimod modulates microglial activation to augment markers of remyelination

INTRODUCTION: Microglial activation in multiple sclerosis has been postulated to contribute to long-term neurodegeneration during disease. Fingolimod has been shown to impact on the relapsing remitting phase of disease by modulating autoreactive T-cell egress from lymph organs. In addition, it is br...

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Detalhes bibliográficos
Main Authors: Jackson, Samuel J, Giovannoni, Gavin, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152910/
https://ncbi.nlm.nih.gov/pubmed/21729281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-8-76
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