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Glycosylation and Processing of Pro-B-type Natriuretic Peptide in Cardiomyocytes

B-type natriuretic peptide (BNP) and its related peptides are biomarkers for the diagnosis of heart failure. Recent studies identified several O-glycosylation sites, including Thr-71, on human pro-BNP but the functional significance was unclear. In this study, we analyzed glycosylation and proteolyt...

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Detalhes bibliográficos
Main Authors: Peng, Jianhao, Jiang, Jingjing, Wang, Wei, Qi, Xiaofei, Sun, Xue-Long, Wu, Qingyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152652/
https://ncbi.nlm.nih.gov/pubmed/21763278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.06.192
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