Paracrine SLPI Secretion Upregulates MMP-9 Transcription and Secretion in Ovarian Cancer Cells

OBJECTIVES: Secretory leukocyte protease inhibitor (SLPI) is amplified in serous ovarian cancer. We have dissected its function, showing it is a survival factor for ovarian cancer and promotes tumorigenesis and paclitaxel-resistance. We hypothesized that the protease inhibitory function was responsi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hoskins, Ebony, Rodriguez-Canales, Jaime, Hewitt, Stephen M., Elmasri, Wafic, Han, Jasmine, Han, Shing, Davidson, Ben, Kohn, Elise C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152651/
https://ncbi.nlm.nih.gov/pubmed/21676452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.04.052
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