Proteomic Biomarkers Apolipoprotein A1, Truncated Transthyretin and Connective Tissue Activating Protein III Enhance the Sensitivity of CA125 for Detecting Early Stage Epithelial Ovarian Cancer

OBJECTIVE: The low prevalence of ovarian cancer demands both high sensitivity (>75%) and specificity (99.6%) to achieve a positive predictive value of 10% for successful early detection. Utilizing a two stage strategy where serum marker(s) prompt the performance of transvaginal sonography (TVS) i...

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Autores principales: Clarke, Charlotte H., Yip, Christine, Badgwell, Donna, Fung, Eric T., Coombes, Kevin R., Zhang, Zhen, Lu, Karen H., Bast, Robert C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152646/
https://ncbi.nlm.nih.gov/pubmed/21708402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2011.06.002
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