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Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism

We have shown previously that during branching morphogenesis of the mouse prostate gland, Bone morphogenetic protein 7 functions to restrict Notch1-positive progenitor cells to the tips of the prostate buds. Here, we employed prostate-specific murine bi-genic systems to investigate the effects of ga...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wu, Xinyu, Xu, Kun, Zhang, Lixia, Deng, Yan, Lee, Peng, Shapiro, Ellen, Monaco, Marie, Makarenkova, Helen P., Li, Juan, Lepor, Herbert, Grishina, Irina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152294/
https://ncbi.nlm.nih.gov/pubmed/21624358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.05.659
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