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BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling

The mouse prostate gland develops by branching morphogenesis from the urogenital epithelium and mesenchyme. Androgens and developmental factors, including FGF10 and SHH, promote prostate growth, while BMP4 signaling from the mesenchyme has been shown to suppresses prostate branching. Here, we show t...

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Detalhes bibliográficos
Main Authors: Grishina, Irina B., Kim, Sung Yup, Ferrara, Christopher, Makarenkova, Helen P., Walden, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644052/
https://ncbi.nlm.nih.gov/pubmed/16324690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2005.08.018
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