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CTL Induction of Tumoricidal Nitric Oxide Production by Intratumoral Macrophages Is Critical for Tumor Elimination

To characterize mechanisms of CTL inhibition within an ocular tumor microenvironment, tumor-specific CTLs were transferred into mice with tumors developing within the anterior chamber of the eye or skin. Ocular tumors were resistant to CTL transfer therapy whereas skin tumors were sensitive. CTLs in...

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Main Authors: Vicetti Miguel, Rodolfo D., Cherpes, Thomas L., Watson, Leah J., McKenna, Kyle C.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152256/
https://ncbi.nlm.nih.gov/pubmed/21041723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903411
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