Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement

Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase that plays a critical role in cell motility. Movement and retraction of podocyte foot processes, which accompany podocyte injury, suggest focal adhesion disassembly. To understand better the mechanisms by which podocyte foot process efface...

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Hlavní autoři: Ma, Hong, Togawa, Akashi, Soda, Keita, Zhang, Junhui, Lee, Sik, Ma, Ming, Yu, Zhiheng, Ardito, Thomas, Czyzyk, Jan, Diggs, Lonnette, Joly, Dominique, Hatakeyama, Shinji, Kawahara, Eiji, Holzman, Lawrence, Guan, Jun Lin, Ishibe, Shuta
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2010
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152231/
https://ncbi.nlm.nih.gov/pubmed/20522532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009090991
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