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Retinoic acid enhances TRAIL induced apoptosis in cancer cells by upregulating TRAIL receptor 1 expression
Many human cancer cells are sensitive to killing by the pro-apoptotic ligand TRAIL which is under study for cancer treatment in clinical trials. The TRAIL receptor TRAIL-R1 (also known as DR4) is a transmembrane receptor that mediates TRAIL-induced apoptosis in cancer cells. In this study, we show t...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151668/ https://ncbi.nlm.nih.gov/pubmed/21685476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-4180 |
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