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Directed conversion of Alzheimer’s disease patient skin fibroblasts into functional neurons
Directed conversion of mature human cells, as from fibroblasts to neurons, would be of potential clinical utility for neurological disease modeling and as cell therapeutics. Here we describe the efficient generation of induced neuronal (hiN) cells from adult skin fibroblasts of unaffected individual...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151530/ https://ncbi.nlm.nih.gov/pubmed/21816272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.07.007 |
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