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The Rb Pathway and Cancer Therapeutics

The retinoblastoma gene, Rb, was originally identified as the tumor suppressor gene mutated in a rare childhood cancer called retinoblastoma (reviewed in [1]. Subsequent studies showed that Rb functions in a pathway that is often functionally inactivated in a large majority of human cancers. Interes...

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Detalhes bibliográficos
Main Authors: Du, Wei, Searle, Jennifer S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151466/
https://ncbi.nlm.nih.gov/pubmed/19601762
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