Cross-Reactivity of Anthrax and C2 Toxin: Protective Antigen Promotes the Uptake of Botulinum C2I Toxin into Human Endothelial Cells

Binary toxins are among the most potent bacterial protein toxins performing a cooperative mode of translocation and exhibit fatal enzymatic activities in eukaryotic cells. Anthrax and C2 toxin are the most prominent examples for the AB(7/8) type of toxins. The B subunits bind both host cell receptor...

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Bibliographische Detailangaben
Hauptverfasser: Kronhardt, Angelika, Rolando, Monica, Beitzinger, Christoph, Stefani, Caroline, Leuber, Michael, Flatau, Gilles, Popoff, Michel R., Benz, Roland, Lemichez, Emmanuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151279/
https://ncbi.nlm.nih.gov/pubmed/21850257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023133
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