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Neutrophils Activate Alveolar Macrophages by producing Caspase-6 Mediated Cleavage of Interleukin-1 Associated Kinase-M (IRAK-M)
Alveolar macrophages (AM) are exposed to respirable microbial particles. Similar to phagocytes in the gastrointestinal tract, AM can suppress inflammation after exposure to nonpathogenic organisms. IRAK-M is one inhibitor of innate immunity, normally suppressing pulmonary inflammation. During pneumo...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151149/ https://ncbi.nlm.nih.gov/pubmed/21098228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001906 |
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