β-Arrestin-1 Protein Represses Adipogenesis and Inflammatory Responses through Its Interaction with Peroxisome Proliferator-activated Receptor-γ (PPARγ)

One of the master regulators of adipogenesis and macrophage function is peroxisome proliferator-activated receptor-γ (PPARγ). Here, we report that a deficiency of β-arrestin-1 expression affects PPARγ-mediated expression of lipid metabolic genes and inflammatory genes. Further mechanistic studies re...

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Detalhes bibliográficos
Main Authors: Zhuang, Le-nan, Hu, Wen-xiang, Xin, Shun-mei, Zhao, Jian, Pei, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151083/
https://ncbi.nlm.nih.gov/pubmed/21700709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256099
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