Synergistic Interactions between Heregulin and Peroxisome Proliferator-activated Receptor-γ (PPARγ) Agonist in Breast Cancer Cells

Here, we demonstrate that troglitazone (Rezulin), a peroxisome proliferator-activated receptor agonist, acted in synergy with heregulin to induce massive cell death in breast cancer cells. Although the combination of heregulin and troglitazone (HRG/TGZ) induced both apoptosis and necrosis, the main...

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Autores principales: Park, Bae-Hang, Lee, Sean-Bong, Stolz, Donna B., Lee, Yong J., Lee, Byeong-Chel
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103381/
https://ncbi.nlm.nih.gov/pubmed/21467033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.191718
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