Accumulation of the Raf-1 Kinase Inhibitory Protein (Rkip) Is Associated with Cep290-mediated Photoreceptor Degeneration in Ciliopathies

Primary cilia regulate polarized protein trafficking in photoreceptors, which are dynamic and highly compartmentalized sensory neurons of retina. The ciliary protein Cep290 modulates cilia formation and is frequently mutated in syndromic and non-syndromic photoreceptor degeneration. However, the und...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Murga-Zamalloa, Carlos A., Ghosh, Amiya K., Patil, Suresh B., Reed, Nathan A., Chan, Lan Sze, Davuluri, Supriya, Peränen, Johan, Hurd, Toby W., Rachel, Rivka A., Khanna, Hemant
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151072/
https://ncbi.nlm.nih.gov/pubmed/21685394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237560
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы