Inhibitor of Cyclin-dependent Kinase (CDK) Interacting with Cyclin A1 (INCA1) Regulates Proliferation and Is Repressed by Oncogenic Signaling

The cell cycle is driven by the kinase activity of cyclin·cyclin-dependent kinase (CDK) complexes, which is negatively regulated by CDK inhibitor proteins. Recently, we identified INCA1 as an interaction partner and a substrate of cyclin A1 in complex with CDK2. On a functional level, we identified...

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Detalhes bibliográficos
Main Authors: Bäumer, Nicole, Tickenbrock, Lara, Tschanter, Petra, Lohmeyer, Lisa, Diederichs, Sven, Bäumer, Sebastian, Skryabin, Boris V., Zhang, Feng, Agrawal-Singh, Shuchi, Köhler, Gabriele, Berdel, Wolfgang E., Serve, Hubert, Koschmieder, Steffen, Müller-Tidow, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151066/
https://ncbi.nlm.nih.gov/pubmed/21540187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203471
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