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G Protein Binding Sites on Calnuc (Nucleobindin 1) and NUCB2 (Nucleobindin 2) Define a New Class of Gα(i)-regulatory Motifs

Heterotrimeric G proteins are molecular switches modulated by families of structurally and functionally related regulators. GIV (Gα-interacting vesicle-associated protein) is the first non-receptor guanine nucleotide exchange factor (GEF) that activates Gα(i) subunits via a defined, evolutionarily c...

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Detaylı Bibliyografya
Asıl Yazarlar: Garcia-Marcos, Mikel, Kietrsunthorn, Patrick S., Wang, Honghui, Ghosh, Pradipta, Farquhar, Marilyn G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151059/
https://ncbi.nlm.nih.gov/pubmed/21653697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.204099
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