Consequences of Loss of Vph1 Protein-containing Vacuolar ATPases (V-ATPases) for Overall Cellular pH Homeostasis

In yeast cells, subunit a of the vacuolar proton pump (V-ATPase) is encoded by two organelle-specific isoforms, VPH1 and STV1. V-ATPases containing Vph1 and Stv1 localize predominantly to the vacuole and the Golgi apparatus/endosomes, respectively. Ratiometric measurements of vacuolar pH confirm tha...

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Bibliographic Details
Main Authors: Tarsio, Maureen, Zheng, Huimei, Smardon, Anne M., Martínez-Muñoz, Gloria A., Kane, Patricia M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151054/
https://ncbi.nlm.nih.gov/pubmed/21669878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.251363
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