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Total Synthesis of (–)-Nakadomarin A
[Image: see text] A concise diastereoselective total synthesis of (–)-nakadomarin A has been completed in 21 steps from D-pyroglutamic acid. Key steps include an enecarbamate Michael addition/furan-N-acyliminium ion cascade cyclization to provide the tetracyclic core, and ring-closing alkyne and alk...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3151009/ https://ncbi.nlm.nih.gov/pubmed/20932022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol102079z |
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