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Initial efforts toward the optimization of arylomycins for antibiotic activity

While most clinically used antibiotics were derived from natural products, the isolation of new broad-spectrum natural products has become increasingly rare and narrow-spectrum agents are typically deemed unsuitable for development due to intrinsic limitations of their scaffold or target. However, i...

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Detalhes bibliográficos
Main Authors: Roberts, Tucker C., Schallenberger, Mark A., Liu, Jian, Smith, Peter A., Romesberg, Floyd E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151006/
https://ncbi.nlm.nih.gov/pubmed/21630667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1016126
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