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The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated
There is a wide variation among humans and mice in airway hyperresponsiveness (AHR) in the absence of allergen sensitization, i.e., naïve AHR. Because mast cell (MC) activation is thought to mediate AHR in atopic asthmatic subjects, we asked whether MCs mediate naïve AHR in A/J mice. We generated an...
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| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150901/ https://ncbi.nlm.nih.gov/pubmed/21768379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106582108 |
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