The naïve airway hyperresponsiveness of the A/J mouse is Kit-mediated

There is a wide variation among humans and mice in airway hyperresponsiveness (AHR) in the absence of allergen sensitization, i.e., naïve AHR. Because mast cell (MC) activation is thought to mediate AHR in atopic asthmatic subjects, we asked whether MCs mediate naïve AHR in A/J mice. We generated an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cozzi, Emily, Ackerman, Kate G., Lundequist, Anders, Drazen, Jeffrey M., Boyce, Joshua A., Beier, David R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150901/
https://ncbi.nlm.nih.gov/pubmed/21768379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106582108
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