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Syntheses of 5-Formyl- and 5-Carboxyl-dC Containing DNA Oligos as Potential Oxidation Products of 5-Hydroxymethylcytosine in DNA

[Image: see text] To investigate the potential oxidation products of 5-hydroxymethylcytosine (5-hmC)-containing DNA, we present here efficient syntheses of 5-formyl- and 5-methoxycarbonyl-2′-deoxycytidine phosphoramidites. The 5-formyl group in III was easy to introduce and was compatible with phosp...

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Bibliografiske detaljer
Main Authors: Dai, Qing, He, Chuan
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150843/
https://ncbi.nlm.nih.gov/pubmed/21648398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201189n
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