Activation of Corticotropin-Releasing Factor Receptor 2 Mediates the Colonic Motor Coping Response to Acute Stress in Rodents

BACKGROUND & AIMS: Corticotropin-releasing factor receptor-1 (CRF1) mediates the stress-induced colonic motor activity. Less is known about the role of CRF2 in the colonic response to stress. METHODS: We studied colonic contractile activity (CCA) in rats and CRF2-/-, CRF-overexpressing, and wild...

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Hauptverfasser: Gourcerol, Guillaume, Wu, S. Vincent, Yuan, Pu-Qing, Pham, Hung, Miampamba, Marcel, Larauche, Muriel, Sanders, Paul, Amano, Tomofumi, Mulak, Agata, Im, Eunok, Pothoulakis, Charalabos, Rivier, Jean, Taché, Yvette, Million, Mulugeta
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150547/
https://ncbi.nlm.nih.gov/pubmed/21277852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2011.01.039
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