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Lack of substrate inhibition in a monomeric form of human cytosolic SULT2A1

Mammalian cytosolic sulfotransferases (SULTs) frequently show substrate inhibition during the sulfation of increasing concentrations of substrates. SULT2A1, a major human liver isoform responsible for the conjugation of hydroxysteroids, bile acids and aliphatic hydroxyl groups in drugs and xenobioti...

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Hlavní autoři: Cook, Ian T., Leyh, Thomas S., Kadlubar, Susan A., Falany, Charles N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150496/
https://ncbi.nlm.nih.gov/pubmed/21822453
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