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TNF-α Signaling in Glaucomatous Neurodegeneration
Growing evidence supports the role of TNF-α as a mediator of neurodegeneration in glaucoma. Glial production of TNF-α is increased and its death receptor is up-regulated on retinal ganglion cells (RGCs) and optic nerve axons in glaucomatous eyes. This multifunctional cytokine can induce RGC death th...
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150483/ https://ncbi.nlm.nih.gov/pubmed/18929124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0079-6123(08)01128-X |
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