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TNF-α Signaling in Glaucomatous Neurodegeneration

Growing evidence supports the role of TNF-α as a mediator of neurodegeneration in glaucoma. Glial production of TNF-α is increased and its death receptor is up-regulated on retinal ganglion cells (RGCs) and optic nerve axons in glaucomatous eyes. This multifunctional cytokine can induce RGC death th...

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Detalhes bibliográficos
Autor principal: Tezel, Gülgün
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150483/
https://ncbi.nlm.nih.gov/pubmed/18929124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0079-6123(08)01128-X
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