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Role of tissue transglutaminase 2 in the acquisition of a mesenchymal-like phenotype in highly invasive A431 tumor cells
BACKGROUND: Cancer progression is closely linked to the epithelial-mesenchymal transition (EMT) process. Studies have shown that there is increased expression of tissue tranglutaminase (TG2) in advanced invasive cancer cells. TG2 catalyzes the covalent cross-linking of proteins, exhibits G protein a...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
BioMed Central
2011
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150327/ https://ncbi.nlm.nih.gov/pubmed/21777419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-10-87 |
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