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Choice of population structure informative principal components for adjustment in a case-control study

BACKGROUND: There are many ways to perform adjustment for population structure. It remains unclear what the optimal approach is and whether the optimal approach varies by the type of samples and substructure present. The simplest and most straightforward approach is to adjust for the continuous prin...

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Detalhes bibliográficos
Main Authors: Peloso, Gina M, Lunetta, Kathryn L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150322/
https://ncbi.nlm.nih.gov/pubmed/21771328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-12-64
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