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GVL against mouse BC-CML and CP-CML: Shared mechanisms of T cell killing, but PD-ligands render CP-CML and not BC-CML GVL-resistant

GVL against chronic phase CML (CP-CML) is potent, but it is less efficacious against acute leukemias and blast crisis CML (BC-CML). The mechanisms underlying GVL-resistance are unknown. Previously, we found that alloreactive T cell targeting of GVL-sensitive bcr-abl-induced mouse CP-CML (mCP-CML) re...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Matte-Martone, Catherine, Venkatesan, Srividhya, Tan, Hung Sheng, Athanasiadis, Ioanna, Chang, Julia, Pavisic, Jovana, Shlomchik, Warren
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3150287/
https://ncbi.nlm.nih.gov/pubmed/21768400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100311
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