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GVL against mouse BC-CML and CP-CML: Shared mechanisms of T cell killing, but PD-ligands render CP-CML and not BC-CML GVL-resistant
GVL against chronic phase CML (CP-CML) is potent, but it is less efficacious against acute leukemias and blast crisis CML (BC-CML). The mechanisms underlying GVL-resistance are unknown. Previously, we found that alloreactive T cell targeting of GVL-sensitive bcr-abl-induced mouse CP-CML (mCP-CML) re...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3150287/ https://ncbi.nlm.nih.gov/pubmed/21768400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100311 |
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