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Interleukin-7 inhibits tumor-induced CD27(−)CD28(−) suppressor T-cells: implications for cancer immunotherapy

PURPOSE: We have previously reported that many types of tumors are able to induce changes in human T cells that lead to the acquisition of suppressive function as well as phenotypic alterations resembling those found in senescent T cells. In the present study we find a role for IL-7 in protecting T...

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Detalhes bibliográficos
Main Authors: Zhang, Yue, Pfannenstiel, Lukas W., Bolesta, Elzbieta, Montes, Carolina, Zhang, Xiaoyu, Chopaval, Andrei I., Gartenhaus, Ronald, Strome, Scott E., Gastman, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149850/
https://ncbi.nlm.nih.gov/pubmed/21712448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3328
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