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Rational engineering of antibody therapeutics targeting multiple oncogene pathways
Monoclonal antibodies have significantly advanced our ability to treat cancer, yet clinical studies have shown that many patients do not adequately respond to monospecific therapy. This is in part due to the multifactorial nature of the disease, where tumors rely on multiple and often redundant path...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149710/ https://ncbi.nlm.nih.gov/pubmed/21393992 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15299 |
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