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Rational engineering of antibody therapeutics targeting multiple oncogene pathways

Monoclonal antibodies have significantly advanced our ability to treat cancer, yet clinical studies have shown that many patients do not adequately respond to monospecific therapy. This is in part due to the multifactorial nature of the disease, where tumors rely on multiple and often redundant path...

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Bibliografski detalji
Glavni autori: Fitzgerald, Jonathan, Lugovskoy, Alexey
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149710/
https://ncbi.nlm.nih.gov/pubmed/21393992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15299
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