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Rational engineering of antibody therapeutics targeting multiple oncogene pathways

Monoclonal antibodies have significantly advanced our ability to treat cancer, yet clinical studies have shown that many patients do not adequately respond to monospecific therapy. This is in part due to the multifactorial nature of the disease, where tumors rely on multiple and often redundant path...

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Detalhes bibliográficos
Main Authors: Fitzgerald, Jonathan, Lugovskoy, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149710/
https://ncbi.nlm.nih.gov/pubmed/21393992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15299
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