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Fragmentation of monoclonal antibodies

Fragmentation is a degradation pathway ubiquitously observed in proteins despite the remarkable stability of peptide bond; proteins differ only by how much and where cleavage occurs. The goal of this review is to summarize reports regarding the non-enzymatic fragmentation of the peptide backbone of...

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Autors principals: Vlasak, Josef, Ionescu, Roxana
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149706/
https://ncbi.nlm.nih.gov/pubmed/21487244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.3.3.15608
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