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Regulation of autophagy by lysosomal positioning

The mammalian target of rapamycin (mTOR) is a well-conserved negative regulator of autophagy. Here we review our recent data describing how lysosomal positioning influences and coordinates mTOR activity, autophagosome biogenesis and autophagosome-lysosome fusion. In this way, lysosomal positioning r...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Korolchuk, Viktor I, Rubinsztein, David C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149695/
https://ncbi.nlm.nih.gov/pubmed/21521941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.8.15862
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