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Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis
Beclin 1, a tumor suppressor protein, acts as an initiator of autophagy in mammals. Heterozygous disruption of Beclin 1 accelerates tumor growth, but the underlying mechanisms remain unclear. We examined the role of Beclin 1 in tumor proliferation and angiogenesis, using a primary mouse melanoma tum...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149693/ https://ncbi.nlm.nih.gov/pubmed/21685724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.8.15598 |
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