Mode of Action of Antibiotic U-20,661
Antibiotic U-20,661 was shown to inhibit predominantly deoxyribonucleic acid (DNA)-directed ribonucleic acid (RNA) synthesis by binding to the double-stranded DNA template. Specific binding to DNA was verified by difference spectroscopy, reversal of the RNA polymerase inhibitory effect by increasing...
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| Published in: | J Bacteriol |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1967
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC314969/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4960159/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.93.1.65-70.1967 |
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