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Mode of Action of Antibiotic U-20,661

Antibiotic U-20,661 was shown to inhibit predominantly deoxyribonucleic acid (DNA)-directed ribonucleic acid (RNA) synthesis by binding to the double-stranded DNA template. Specific binding to DNA was verified by difference spectroscopy, reversal of the RNA polymerase inhibitory effect by increasing...

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Detalhes bibliográficos
Autor principal: Reusser, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: 1967
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC314969/
https://ncbi.nlm.nih.gov/pubmed/4960159
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