Modulation of Glucose Transporter 1 (GLUT1) Expression Levels Alters Mouse Mammary Tumor Cell Growth In Vitro and In Vivo

Tumor cells exhibit an altered metabolism characterized by elevated aerobic glycolysis and lactate secretion which is supported by an increase in glucose transport and consumption. We hypothesized that reducing or eliminating the expression of the most prominently expressed glucose transporter(s) wo...

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Main Authors: Young, Christian D., Lewis, Andrew S., Rudolph, Michael C., Ruehle, Marisa D., Jackman, Matthew R., Yun, Ui J., Ilkun, Olesya, Pereira, Renata, Abel, E. Dale, Anderson, Steven M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149640/
https://ncbi.nlm.nih.gov/pubmed/21826239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023205
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