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Checkpoints in Adenoviral Production: Cross-Contamination and E1A
Adenoviruses are widely used for overexpressing proteins in primary mammalian cells. Incorporation of the early viral gene, E1A, or viral cross-contamination can occur during amplification, and identification of these products is crucial as the transcription of unwanted genetic material can impact c...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149638/ https://ncbi.nlm.nih.gov/pubmed/21826235 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023160 |
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