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Quantitative evaluation of all hexamers as exonic splicing elements
We describe a comprehensive quantitative measure of the splicing impact of a complete set of RNA 6-mer sequences by deep sequencing successfully spliced transcripts. All 4096 6-mers were substituted at five positions within two different internal exons in a 3-exon minigene, and millions of successfu...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149502/ https://ncbi.nlm.nih.gov/pubmed/21659425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119628.110 |
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