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Quantitative evaluation of all hexamers as exonic splicing elements

We describe a comprehensive quantitative measure of the splicing impact of a complete set of RNA 6-mer sequences by deep sequencing successfully spliced transcripts. All 4096 6-mers were substituted at five positions within two different internal exons in a 3-exon minigene, and millions of successfu...

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Bibliografske podrobnosti
Main Authors: Ke, Shengdong, Shang, Shulian, Kalachikov, Sergey M., Morozova, Irina, Yu, Lin, Russo, James J., Ju, Jingyue, Chasin, Lawrence A.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149502/
https://ncbi.nlm.nih.gov/pubmed/21659425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.119628.110
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