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Efficacy of Tat-Conjugated Ritonavir-Loaded Nanoparticles in Reducing HIV-1 Replication in Monocyte-Derived Macrophages and Cytocompatibility with Macrophages and Human Neurons

Human immunodeficiency virus (HIV)-1 targets mononuclear phagocytes (MP), which disseminate infection to organs such as brain, spleen and lymph. Thus MP, which include microglia, tissue macrophages and infiltrating monocyte-derived macrophages (MDM), are important target of anti-HIV-1 drug therapy....

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Autors principals: Borgmann, Kathleen, Rao, Kavitha S., Labhasetwar, Vinod, Ghorpade, Anuja
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149452/
https://ncbi.nlm.nih.gov/pubmed/21175357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2010.0295
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