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TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs
We have shown that nanoparticles (NPs) conjugated to trans-activating transcriptor (TAT) peptide bypass the efflux action of P-glycoprotein and increases the transport of the encapsulated ritonavir, a protease inhibitor (PI), across the blood-brain-barrier (BBB) to the central nervous system (CNS)....
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2570783/ https://ncbi.nlm.nih.gov/pubmed/18760470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.08.004 |
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