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R1 in the Shaker S4 occupies the gating charge transfer center in the resting state
During voltage-dependent activation in Shaker channels, four arginine residues in the S4 segment (R1–R4) cross the transmembrane electric field. It has been proposed that R1–R4 movement is facilitated by a “gating charge transfer center” comprising a phenylalanine (F290) in S2 plus two acidic residu...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149438/ https://ncbi.nlm.nih.gov/pubmed/21788609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110642 |
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