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Local constraints in either the GluN1 or GluN2 subunit equally impair NMDA receptor pore opening
The defining functional feature of N-methyl-d-aspartate (NMDA) receptors is activation gating, the energetic coupling of ligand binding into opening of the associated ion channel pore. NMDA receptors are obligate heterotetramers typically composed of glycine-binding GluN1 and glutamate-binding GluN2...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3149435/ https://ncbi.nlm.nih.gov/pubmed/21746848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110623 |
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