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Perturbation of BRD4 Protein Function by BRD4-NUT Protein Abrogates Cellular Differentiation in NUT Midline Carcinoma

NUT midline carcinoma (NMC) belongs to a class of highly lethal and poorly differentiated epithelial cancers arising mainly in human midline organs. NMC is caused by the chromosome translocation-mediated fusion of the NUT (nuclear protein in testis) gene on chromosome 15 to a few other genes, most f...

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Main Authors: Yan, Junpeng, Diaz, Jason, Jiao, Jing, Wang, Ranran, You, Jianxin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149357/
https://ncbi.nlm.nih.gov/pubmed/21652721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.246975
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