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Apolipoprotein L6, Induced in Atherosclerotic Lesions, Promotes Apoptosis and Blocks Beclin 1-dependent Autophagy in Atherosclerotic Cells

Inflammatory cytokine-regulated apoptosis and autophagy play pivotal roles in plaque rupture and thrombosis of atherosclerotic lesions. However, the molecular interplay between apoptosis and autophagy in vascular cells has not been investigated. Our prior study showed that human apolipoprotein L6 (A...

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Bibliografske podrobnosti
Main Authors: Zhaorigetu, Siqin, Yang, Zhaoqing, Toma, Ian, McCaffrey, Timothy A., Hu, Chien-An A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149332/
https://ncbi.nlm.nih.gov/pubmed/21646352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.210245
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