17β-Estradiol suppresses Helicobacter pylori-induced gastric pathology in male hypergastrinemic INS-GAS mice

Helicobacter pylori-associated gastric cancer is male predominant and animal studies suggest that sex hormones influence gastric carcinogenesis. We investigated the effects of 17β-estradiol (E2) or castration on H.pylori-induced gastritis in male INS-GAS/FVB/N (Tg(Ins1-GAS)1Sbr) mice. Comparisons we...

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Main Authors: Ohtani, Masahiro, Ge, Zhongming, García, Alexis, Rogers, Arlin B., Muthupalani, Sureshkumar, Taylor, Nancy S., Xu, Shilu, Watanabe, Koichiro, Feng, Yan, Marini, Robert P., Whary, Mark T., Wang, Timothy C., Fox, James G.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Cancer Prevention
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149202/
https://ncbi.nlm.nih.gov/pubmed/21565825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr072
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